Patents

US 6,653,327

Cross-regulin composition of turmeric-derived Tetrahydrocurcuminoids for skin lightening and protection against UVB rays

Abstract: The present invention is directed to a mixture of tetrahydrocurcuminoids which can be used for regulating random, intracellular protein cross-linking an optimizing cell electric potential in a patient.

US 5,861,415

Bioprotectant composition, method of use and extraction process of curcuminoids

Abstract: Curcuminoids have been found to have anti-oxidant, anti-inflammatory, antibacterial, antifungal, antiparasitic, anti-mutagen, anticancer and detox properties. The present invention is directed to compositions containing three curcuminoids, i.e. curcumin, demethoxy curcumin and bis demethoxy curcumin, extracted from roots of tumeric. These compositions have been found to have activity in the anti-oxidant mechanisms of prevention and intervention.

US 7,521,580

Novel Non-cytotoxic synthetic analogues of (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3, 5-dione and therapeutic applications thereof in cystic fibrosis)

Abstract: Disclosed are novel, synthetic analogues of (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione and the therapeutic applications for cystic fibrosis thereof in correcting altered CFTR trafficking and the associated impaired chloride (Cl−) ion transport. Introduction of branched-alkyl groups ortho to the phenolic groups gave rise to clinical compounds with vastly improved trafficking of delF508CFTR and with no cytotoxicity.

US 8,119,696

Treatment of superficial and cutaneous mycoses with a pure form of 1,7-bis(4-hydroxy-3-methoxyphenyl)-3,5-heptanedione

Abstract: Disclosed are novel and enhanced anti-fungal properties of greater than 99% pure form of 1,7-Bis(4-hydroxy-3-methoxyphenyl)-3,5-heptanedione in comparison with the corresponding 95% pure form, said greater than 99% pure form of 1,7-Bis(4-hydroxy-3-methoxyphenyl)-3,5-heptanedione being devoid of 5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-3-heptanone and 3,5-Dihydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-heptane. The inventors disclose the uses of greater than 99% pure form of 1,7-Bis(4-hydroxy-3-methoxyphenyl)-3,5-heptanedione as anti-fungal agents capable of inhibiting superficial and cutaneous mycoses in humans and treatment methods thereof.; Also disclosed is the enhanced potential of greater than 99% pure form of 1,7-Bis(4-hydroxy-3-methoxyphenyl)-3,5-heptanedione as compared to the corresponding 95% pure form against bacterial and fungal phytopathogens and applications thereof in agriculture.

AU2006235807

Use of tetrahydrocurcuminoids to regulate physiological and pathological events in the skin and mucosa

Abstract: The present invention is directed to a mixture of tetrahydrocurcuminoids which can be used for regulating random intracellular protein crosslinking, optimizing cell electric potential, treating a premalignant state or malignancy, increasing intracellular transglutaminase activity, and reducing “age spots” due to lipofunction formation.

EP1328263

Process of making and method of use of Tetrahydrocurcuminoids to regulate physiological and pathological events in the skin and mucosa cells

Abstract: The present invention is directed to a mixture of tetrahydrocurcuminoids which can be used for regulating random intracellular protein crosslinking, optimizing cell electric potential, treating a premalignant state or a malignancy, increasing intracellular transglutaminase activity, and reducing “age spots” due to lipofunction formation.

EP1171144

Use of Tetrahydrocurcuminoids to regulate physiological and pathological events in the skin and mucosa

Abstract: The present invention is directed to a mixture of tetrahydrocurcuminoids which can be used for regulating random intracellular protein crosslinking, optimizing cell electric potential, treating a premalignant state or a malignancy, increasing intracellular transglutaminase activity, and reducing “age spots” due to lipofunction formation.

EP0839037

Bioprotectant composition, method of use and extraction process of Curcuminoids

Abstract: Curcuminoids have been found to have anti-oxidant, anti-inflammatory, antibacterial, antifungal, antiparasitic, anti-mutagen, anticancer and detox properties. The present invention is directed to compositions containing three curcuminoids, i.e. curcumin, demethoxy curcumin and bis demethoxy curcumin, extracted from roots of tumeric. These compositions have been found to have activity in the anti-oxidant mechanisms of prevention and intervention.

NZ514884

Use of Tetrahydrocurcuminoids to regulate physiological and pathological events in the skin and mucosa

Abstract: A mixture of tetrahydrocurcuminoids comprising 75-85% tetrahydrocurcumin, 10-20% tetrahydrodemethoxycurcumin and 2.0-4.5% tetrahydrobismethoxycurcumin, its use to treat skin malignancy including melanoma, or skin inflammation and a method of treating age spots.